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“TRUPATH, an Open-Source Biosensor Platform for Interrogating the GPCR Transducerome”

G protein-coupled receptors (GPCRs) remain major drug targets despite our incomplete understanding of how they signal through 16 non-visual G protein signal transducers (collectively named the transducerome) to exert their actions. To address this gap, we developed an open-source suite of 14 optimiz...

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Detalles Bibliográficos
Autores principales: Olsen, Reid H.J., DiBerto, Jeffrey F., English, Justin G., Glaudin, Alexis M., Krumm, Brian E., Slocum, Samuel T., Che, Tao, Gavin, Ariana C., McCorvy, John D., Roth, Bryan L., Strachan, Ryan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648517/
https://www.ncbi.nlm.nih.gov/pubmed/32367019
http://dx.doi.org/10.1038/s41589-020-0535-8