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“TRUPATH, an Open-Source Biosensor Platform for Interrogating the GPCR Transducerome”
G protein-coupled receptors (GPCRs) remain major drug targets despite our incomplete understanding of how they signal through 16 non-visual G protein signal transducers (collectively named the transducerome) to exert their actions. To address this gap, we developed an open-source suite of 14 optimiz...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648517/ https://www.ncbi.nlm.nih.gov/pubmed/32367019 http://dx.doi.org/10.1038/s41589-020-0535-8 |