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Melting dsDNA Donor Molecules Greatly Improves Precision Genome Editing in Caenorhabditis elegans
CRISPR genome editing has revolutionized genetics in many organisms. In the nematode Caenorhabditis elegans, one injection into each of the two gonad arms of an adult hermaphrodite exposes hundreds of meiotic germ cells to editing mixtures, permitting the recovery of multiple indels or small precisi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Genetics Society of America
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648581/ https://www.ncbi.nlm.nih.gov/pubmed/32963112 http://dx.doi.org/10.1534/genetics.120.303564 |