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A modified IRS-III chemotherapy regimen leads to prolonged survival in children with embryonal tumor with multilayer rosettes

BACKGROUND: Embryonal tumor with multilayer rosettes (ETMR) is a rare CNS malignancy affecting young children that carries a very poor prognosis. Treatment with intensive surgical resection, radiotherapy, and high-dose chemotherapy is insufficient treatment in the vast majority of cases. Effective,...

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Detalles Bibliográficos
Autores principales: Hanson, Derek, Hoffman, Lindsey M, Nagabushan, Sumanth, Goumnerova, Liliana C, Rathmann, Allison, Vogel, Timothy, Ziegler, David S, Chi, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648589/
https://www.ncbi.nlm.nih.gov/pubmed/33196040
http://dx.doi.org/10.1093/noajnl/vdaa120