Progenitor death drives retinal dysplasia and neuronal degeneration in a mouse model of ATRIP-Seckel syndrome

Seckel syndrome is a type of microcephalic primordial dwarfism (MPD) that is characterized by growth retardation and neurodevelopmental defects, including reports of retinopathy. Mutations in key mediators of the replication stress response, the mutually dependent partners ATR and ATRIP, are among t...

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Detalles Bibliográficos
Autores principales: Matos-Rodrigues, Gabriel E., Tan, Pedro B., Rocha-Martins, Maurício, Charlier, Clara F., Gomes, Anielle L., Cabral-Miranda, Felipe, Grigaravicius, Paulius, Hofmann, Thomas G., Frappart, Pierre-Olivier, Martins, Rodrigo A. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648607/
https://www.ncbi.nlm.nih.gov/pubmed/32994318
http://dx.doi.org/10.1242/dmm.045807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648607/
https://www.ncbi.nlm.nih.gov/pubmed/32994318
http://dx.doi.org/10.1242/dmm.045807

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