Cargando…
Progenitor death drives retinal dysplasia and neuronal degeneration in a mouse model of ATRIP-Seckel syndrome
Seckel syndrome is a type of microcephalic primordial dwarfism (MPD) that is characterized by growth retardation and neurodevelopmental defects, including reports of retinopathy. Mutations in key mediators of the replication stress response, the mutually dependent partners ATR and ATRIP, are among t...
Autores principales: | Matos-Rodrigues, Gabriel E., Tan, Pedro B., Rocha-Martins, Maurício, Charlier, Clara F., Gomes, Anielle L., Cabral-Miranda, Felipe, Grigaravicius, Paulius, Hofmann, Thomas G., Frappart, Pierre-Olivier, Martins, Rodrigo A. P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648607/ https://www.ncbi.nlm.nih.gov/pubmed/32994318 http://dx.doi.org/10.1242/dmm.045807 |
Ejemplares similares
-
ATRIP protects progenitor cells against DNA damage in vivo
por: Matos-Rodrigues, Gabriel E., et al.
Publicado: (2020) -
Correction: ATRIP protects progenitor cells against DNA damage in vivo
por: Matos-Rodrigues, Gabriel E., et al.
Publicado: (2020) -
Identification of the First ATRIP–Deficient Patient and Novel Mutations in ATR Define a Clinical Spectrum for ATR–ATRIP Seckel Syndrome
por: Ogi, Tomoo, et al.
Publicado: (2012) -
Correction: Nbn and Atm Cooperate in a Tissue and Developmental Stage-Specific Manner to Prevent Double Strand Breaks and Apoptosis in Developing Brain and Eye
por: Rodrigues, Paulo M. G., et al.
Publicado: (2013) -
Seckel-like syndrome or Seckel variants?
por: Cherian, Mathew Punnachalil
Publicado: (2004)