A novel hypomorphic allele of Spag17 causes primary ciliary dyskinesia phenotypes in mice

Primary ciliary dyskinesia (PCD) is a human condition of dysfunctional motile cilia characterized by recurrent lung infection, infertility, organ laterality defects and partially penetrant hydrocephalus. We recovered a mouse mutant from a forward genetic screen that developed many of the hallmark ph...

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Detalles Bibliográficos
Autores principales: Abdelhamed, Zakia, Lukacs, Marshall, Cindric, Sandra, Omran, Heymut, Stottmann, Rolf W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648611/
https://www.ncbi.nlm.nih.gov/pubmed/32988999
http://dx.doi.org/10.1242/dmm.045344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648611/
https://www.ncbi.nlm.nih.gov/pubmed/32988999
http://dx.doi.org/10.1242/dmm.045344

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