Functional redundancy of Burkholderia pseudomallei phospholipase C enzymes and their role in virulence

Phospholipase C (PLC) enzymes are key virulence factors in several pathogenic bacteria. Burkholderia pseudomallei, the causative agent of melioidosis, possesses at least three plc genes (plc1, plc2 and plc3). We found that in culture medium plc1 gene expression increased with increasing pH, whilst e...

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Detalles Bibliográficos
Autores principales: Srinon, Varintip, Withatanung, Patoo, Chaiwattanarungruengpaisan, Somjit, Thongdee, Metawee, Meethai, Chatruthai, Stevens, Joanne M., Titball, Richard W., Korbsrisate, Sunee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648637/
https://www.ncbi.nlm.nih.gov/pubmed/33159122
http://dx.doi.org/10.1038/s41598-020-76186-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648637/
https://www.ncbi.nlm.nih.gov/pubmed/33159122
http://dx.doi.org/10.1038/s41598-020-76186-z

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