Dexmedetomidine Alleviates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting p75NTR-Mediated Oxidative Stress and Apoptosis

Oxidative stress and apoptosis play a key role in the pathogenesis of sepsis-associated acute kidney injury (AKI). Dexmedetomidine (DEX) may present renal protective effects in sepsis. Therefore, we studied antioxidant effects and the mechanism of DEX in an inflammatory proximal tubular epithelial c...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Zhe, Wu, Jiali, Hu, Zhaolan, Luo, Cong, Wang, Pengfei, Zhang, Yanling, Li, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648709/
https://www.ncbi.nlm.nih.gov/pubmed/33194004
http://dx.doi.org/10.1155/2020/5454210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648709/
https://www.ncbi.nlm.nih.gov/pubmed/33194004
http://dx.doi.org/10.1155/2020/5454210

Ejemplares similares