Cargando…

Dexmedetomidine Alleviates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting p75NTR-Mediated Oxidative Stress and Apoptosis

Oxidative stress and apoptosis play a key role in the pathogenesis of sepsis-associated acute kidney injury (AKI). Dexmedetomidine (DEX) may present renal protective effects in sepsis. Therefore, we studied antioxidant effects and the mechanism of DEX in an inflammatory proximal tubular epithelial c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Zhe, Wu, Jiali, Hu, Zhaolan, Luo, Cong, Wang, Pengfei, Zhang, Yanling, Li, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648709/ https://www.ncbi.nlm.nih.gov/pubmed/33194004 http://dx.doi.org/10.1155/2020/5454210

Ejemplares similares

The role and potential mechanism of p75NTR in mineralization via in vivo p75NTR knockout mice and in vitro ectomesenchymal stem cells
por: Zhao, Manzhu, et al.
Publicado: (2020)

Structural Characterization of the Self-Association of the Death Domain of p75(NTR)
por: Qu, Qianhui, et al.
Publicado: (2013)

Dexmedetomidine alleviates lipopolysaccharide-induced lung injury in Wistar rats
por: Yan, Xuetao, et al.
Publicado: (2017)

p75(NTR) in Huntington's disease: beyond the basal ganglia
por: Brito, Verónica, et al.
Publicado: (2015)

Valproic acid upregulates the expression of the p75NTR/sortilin receptor complex to induce neuronal apoptosis
por: Dedoni, Simona, et al.
Publicado: (2020)

Fast-diffusing p75(NTR) monomers support apoptosis and growth cone collapse by neurotrophin ligands
por: Marchetti, Laura, et al.
Publicado: (2019)

Up-Regulation of ProBDNF/p75(NTR) Signaling in Spinal Cord Drives Inflammatory Pain in Male Rats
por: Li, Hui, et al.
Publicado: (2023)

Overexpression of p75(NTR) in Human Seminoma: A New Biomarker?
por: Perri, Anna, et al.
Publicado: (2021)

Plasmalogen attenuates the development of hepatic steatosis and cognitive deficit through mechanism involving p75NTR inhibition
por: Liu, Yanjun, et al.
Publicado: (2021)

Glucose homeostasis and p75(NTR): The sweet side of neurotrophin receptor signaling
por: Baeza-Raja, Bernat, et al.
Publicado: (2012)

p75(NTR), but Not proNGF, Is Upregulated Following Status Epilepticus in Mice
por: VonDran, Melissa W., et al.
Publicado: (2014)

Upregulation of p75NTR by Histone Deacetylase Inhibitors Sensitizes Human Neuroblastoma Cells to Targeted Immunotoxin-Induced Apoptosis
por: Dedoni, Simona, et al.
Publicado: (2022)

Self-renewal and chemotherapy resistance of p75(NTR )positive cells in esophageal squamous cell carcinomas
por: Huang, Sheng-Dong, et al.
Publicado: (2009)

Up-regulation of proBDNF/p75(NTR) signaling in antibody-secreting cells drives systemic lupus erythematosus
por: Shen, Wei-Yun, et al.
Publicado: (2022)

MAG induces apoptosis in cerebellar granule neurons through p75(NTR) demarcating granule layer/white matter boundary
por: Fernández-Suárez, Diana, et al.
Publicado: (2019)

p75NTR promotes tooth rhythmic mineralization via upregulation of BMAL1/CLOCK
por: Xie, Bo, et al.
Publicado: (2023)

Rabies Virus Hijacks and Accelerates the p75NTR Retrograde Axonal Transport Machinery
por: Gluska, Shani, et al.
Publicado: (2014)

Impaired striatal function in Huntington's disease is due to aberrant p75NTR signaling
por: Plotkin, Joshua L, et al.
Publicado: (2014)

Detection of circulating tumor cells by p75NTR expression in patients with esophageal cancer
por: Yamaguchi, Tetsuji, et al.
Publicado: (2016)

Neurotrophin Receptor p75NTR Regulates Immune Function of Plasmacytoid Dendritic Cells
por: Bandoła, Joanna, et al.
Publicado: (2017)

Peripheral Nerve Regeneration Is Independent From Schwann Cell p75(NTR) Expression
por: Gonçalves, Nádia P., et al.
Publicado: (2019)

SorCS3 promotes the internalization of p75(NTR) to inhibit GBM progression
por: Zhang, Yanqiu, et al.
Publicado: (2022)

The Effect of Interaction NGF/p75(NTR) in Sperm Cells: A Rabbit Model
por: Castellini, Cesare, et al.
Publicado: (2022)

Finding ATF4/p75NTR/IL-8 Signal Pathway in Endothelial–Mesenchymal Transition by Safrole Oxide
por: Ge, Di, et al.
Publicado: (2014)

Caspase-2 and p75 neurotrophin receptor (p75NTR) are involved in the regulation of SREBP and lipid genes in hepatocyte cells
por: Pham, Dan Duc, et al.
Publicado: (2019)

Cholinergic neurodegeneration and cholesterol metabolism dysregulation by constitutive p75(NTR) signaling in the p75(exonIII)-KO mice
por: Comaposada-Baró, Raquel, et al.
Publicado: (2023)

Cortical Brain Injury Causes Retrograde Degeneration of Afferent Basal Forebrain Cholinergic Neurons via the p75NTR
por: Dasgupta, Srestha, et al.
Publicado: (2023)

Dexmedetomidine attenuates lipopolysaccharide-induced acute lung injury by inhibiting oxidative stress, mitochondrial dysfunction and apoptosis in rats
por: Fu, Chunlai, et al.
Publicado: (2017)

Correction: MAG induces apoptosis in cerebellar granule neurons through p75(NTR) demarcating granule layer/white matter boundary
por: Fernández-Suárez, Diana, et al.
Publicado: (2019)

Molecular Mechanism of Switching of TrkA/p75(NTR) Signaling in Monocrotophos Induced Neurotoxicity
por: Kumar, Vivek, et al.
Publicado: (2015)

p75(NTR) antagonists attenuate photoreceptor cell loss in murine models of retinitis pigmentosa
por: Platón-Corchado, María, et al.
Publicado: (2017)

Sexual Dimorphism in Balance and Coordination in p75NTR(exonIII) Knock-Out Mice
por: Abbasian, Mahdi, et al.
Publicado: (2022)

Expression of NGF/proNGF and Their Receptors TrkA, p75(NTR) and Sortilin in Melanoma
por: Marsland, Mark, et al.
Publicado: (2022)

Association of the p75(NTR) Ser205Leu Polymorphism with Asymptomatic HTLV-1 Infection
por: Queiroz, Maria Alice Freitas, et al.
Publicado: (2022)

Glioma invasion mediated by the p75 neurotrophin receptor (p75(NTR)/CD271) requires regulated interaction with PDLIM1
por: Ahn, B Y, et al.
Publicado: (2016)

Activation of neutral-sphingomyelinase, MAPKs, and p75 NTR-mediating caffeic acid phenethyl ester–induced apoptosis in C6 glioma cells
por: Tseng, Tsui-Hwa, et al.
Publicado: (2014)

The p75(NTR) and its carboxyl‐terminal fragment exert opposing effects on melanoma cell proliferation and apoptosis via modulation of the NF‐κB pathway
por: Zhong, Maojiao, et al.
Publicado: (2020)

Schwannomas provide insight into the role of p75(NTR) and merlin in Schwann cells following nerve injury and during regeneration
por: Cheng, Elise, et al.
Publicado: (2016)

2,5-Hexanedione induced apoptosis in rat spinal cord neurons and VSC4.1 cells via the proNGF/p75NTR and JNK pathways
por: Luo, Mengxin, et al.
Publicado: (2021)

Divergent Roles of p75(NTR) and Trk Receptors in BDNF's Effects on Dendritic Spine Density and Morphology
por: Chapleau, Christopher A., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_36mtk7r5518l8asnf01d1m3m51