Application of physiologically based pharmacokinetic modeling for sertraline dosing recommendations in pregnancy

Pregnancy is a period of significant change that impacts physiological and metabolic status leading to alterations in the disposition of drugs. Uncertainty in drug dosing in pregnancy can lead to suboptimal therapy, which can contribute to disease exacerbation. A few studies show there are increased...

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Detalles Bibliográficos
Autores principales: George, Blessy, Lumen, Annie, Nguyen, Christine, Wesley, Barbara, Wang, Jian, Beitz, Julie, Crentsil, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648747/
https://www.ncbi.nlm.nih.gov/pubmed/33159093
http://dx.doi.org/10.1038/s41540-020-00157-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648747/
https://www.ncbi.nlm.nih.gov/pubmed/33159093
http://dx.doi.org/10.1038/s41540-020-00157-3

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