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Application of physiologically based pharmacokinetic modeling for sertraline dosing recommendations in pregnancy
Pregnancy is a period of significant change that impacts physiological and metabolic status leading to alterations in the disposition of drugs. Uncertainty in drug dosing in pregnancy can lead to suboptimal therapy, which can contribute to disease exacerbation. A few studies show there are increased...
Autores principales: | George, Blessy, Lumen, Annie, Nguyen, Christine, Wesley, Barbara, Wang, Jian, Beitz, Julie, Crentsil, Victor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648747/ https://www.ncbi.nlm.nih.gov/pubmed/33159093 http://dx.doi.org/10.1038/s41540-020-00157-3 |
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