In vitro and in vivo BNCT investigations using a carborane containing sulfonamide targeting CAIX epitopes on malignant pleural mesothelioma and breast cancer cells

This study aims at merging the therapeutic effects associated to the inhibition of Carbonic Anhydrase IX (CAIX), an essential enzyme overexpressed by cancer cells including mesothelioma and breast cancer, with those ones brought by the application of Boron Neutron Capture Therapy (BNCT). This task w...

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Detalles Bibliográficos
Autores principales: Alberti, Diego, Michelotti, Alessia, Lanfranco, Alberto, Protti, Nicoletta, Altieri, Saverio, Deagostino, Annamaria, Geninatti Crich, Simonetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648750/
https://www.ncbi.nlm.nih.gov/pubmed/33159147
http://dx.doi.org/10.1038/s41598-020-76370-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648750/
https://www.ncbi.nlm.nih.gov/pubmed/33159147
http://dx.doi.org/10.1038/s41598-020-76370-1

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