Activation of toll like receptor 4 (TLR4) promotes cardiomyocyte apoptosis through SIRT2 dependent p53 deacetylation

Cardiomyocyte inflammation followed by apoptosis and fibrosis is an important mediator for development and progression of heart failure. Activation of toll-like receptor 4 (TLR4), an important regulator of inflammation, causes the progression of cardiac hypertrophy and injury. However, the precise m...

Descripción completa

Detalles Bibliográficos
Autores principales: Katare, Parmeshwar Bajirao, Nizami, Hina Lateef, Paramesha, Bugga, Dinda, Amit K., Banerjee, Sanjay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648754/
https://www.ncbi.nlm.nih.gov/pubmed/33159115
http://dx.doi.org/10.1038/s41598-020-75301-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648754/
https://www.ncbi.nlm.nih.gov/pubmed/33159115
http://dx.doi.org/10.1038/s41598-020-75301-4

Ejemplares similares