Cargando…
Activation of toll like receptor 4 (TLR4) promotes cardiomyocyte apoptosis through SIRT2 dependent p53 deacetylation
Cardiomyocyte inflammation followed by apoptosis and fibrosis is an important mediator for development and progression of heart failure. Activation of toll-like receptor 4 (TLR4), an important regulator of inflammation, causes the progression of cardiac hypertrophy and injury. However, the precise m...
Autores principales: | Katare, Parmeshwar Bajirao, Nizami, Hina Lateef, Paramesha, Bugga, Dinda, Amit K., Banerjee, Sanjay K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648754/ https://www.ncbi.nlm.nih.gov/pubmed/33159115 http://dx.doi.org/10.1038/s41598-020-75301-4 |
Ejemplares similares
-
SIRT-3 Modulation by Resveratrol Improves Mitochondrial Oxidative Phosphorylation in Diabetic Heart through Deacetylation of TFAM
por: Bagul, Pankaj K., et al.
Publicado: (2018) -
Toll-Like Receptor 4 Inhibition Improves Oxidative Stress and Mitochondrial Health in Isoproterenol-Induced Cardiac Hypertrophy in Rats
por: Katare, Parmeshwar B., et al.
Publicado: (2017) -
Musa balbisiana Fruit Rich in Polyphenols Attenuates Isoproterenol-Induced Cardiac Hypertrophy in Rats via Inhibition of Inflammation and Oxidative Stress
por: Kumari, Sima, et al.
Publicado: (2020) -
Sirt1 and Sirt3 Activation Improved Cardiac Function of Diabetic Rats via Modulation of Mitochondrial Function
por: Paramesha, Bugga, et al.
Publicado: (2021) -
SIRT3 Regulates Clearance of Apoptotic Cardiomyocytes by Deacetylating Frataxin
por: Gao, Jing, et al.
Publicado: (2023)