circ-CBFB upregulates p66Shc to perturb mitochondrial dynamics in APAP-induced liver injury

p66Shc, a master regulator of mitochondrial reactive oxygen species (mtROS), is a crucial mediator of hepatocyte oxidative stress. However, its functional contribution to acetaminophen (APAP)-induced liver injury and the mechanism by which it is modulated remain unknown. Here, we aimed to assess the...

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Detalles Bibliográficos
Autores principales: Wang, Zhecheng, Zhao, Yan, Sun, Ruimin, Sun, Yu, Liu, Deshun, Lin, Musen, Chen, Zhao, Zhou, Junjun, Lv, Li, Tian, Xiaofeng, Yao, Jihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648761/
https://www.ncbi.nlm.nih.gov/pubmed/33159035
http://dx.doi.org/10.1038/s41419-020-03160-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648761/
https://www.ncbi.nlm.nih.gov/pubmed/33159035
http://dx.doi.org/10.1038/s41419-020-03160-y

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