Parp3 promotes astrocytic differentiation through a tight regulation of Nox4-induced ROS and mTorc2 activation

Parp3 is a member of the Poly(ADP-ribose) polymerase (Parp) family that has been characterized for its functions in strand break repair, chromosomal rearrangements, mitotic segregation and tumor aggressiveness. Yet its physiological implications remain unknown. Here we report a central function of P...

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Detalles Bibliográficos
Autores principales: Rodriguez-Vargas, José-Manuel, Martin-Hernandez, Kathline, Wang, Wei, Kunath, Nicolas, Suganthan, Rajikala, Amé, Jean-Christophe, Oliver, F. Javier, Ye, Jing, Bjørås, Magnar, Dantzer, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648797/
https://www.ncbi.nlm.nih.gov/pubmed/33159039
http://dx.doi.org/10.1038/s41419-020-03167-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648797/
https://www.ncbi.nlm.nih.gov/pubmed/33159039
http://dx.doi.org/10.1038/s41419-020-03167-5

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