An updated evolutionary study of the Notch family reveals a new ancient origin and novel invariable motifs as potential pharmacological targets

Notch family proteins play a key role in a variety of developmental processes by controlling cell fate decisions and operating in a great number of biological processes in several organ systems, such as hematopoiesis, somatogenesis, vasculogenesis, neurogenesis and homeostasis. The Notch signaling p...

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Detalles Bibliográficos
Autores principales: Vlachakis, Dimitrios, Papageorgiou, Louis, Papadaki, Ariadne, Georga, Maria, Kossida, Sofia, Eliopoulos, Elias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649014/
https://www.ncbi.nlm.nih.gov/pubmed/33194454
http://dx.doi.org/10.7717/peerj.10334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649014/
https://www.ncbi.nlm.nih.gov/pubmed/33194454
http://dx.doi.org/10.7717/peerj.10334

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