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Transdifferentiation of α-1,3-galactosyltransferase knockout pig bone marrow derived mesenchymal stem cells into pancreatic β-like cells by microenvironment modulation

OBJECTIVE: To evaluate the pancreatic differentiation potential of α-1,3-galactosyltransferase knockout (GalTKO) pig-derived bone marrow-derived mesenchymal stem cells (BM-MSCs) using epigenetic modifiers with different pancreatic induction media. METHODS: The BM-MSCs have been differentiated into p...

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Detalles Bibliográficos
Autores principales: Ullah, Imran, Lee, Ran, Oh, Keon Bong, Hwang, Seongsoo, Kim, Youngim, Hur, Tai-Young, Ock, Sun A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asian-Australasian Association of Animal Production Societies (AAAP) and Korean Society of Animal Science and Technology (KSAST) 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649066/
https://www.ncbi.nlm.nih.gov/pubmed/32106662
http://dx.doi.org/10.5713/ajas.19.0796