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The role of m(6)A modification in physiology and disease
Similar to DNA epigenetic modifications, multiple reversible chemical modifications on RNAs have been uncovered in a new layer of epigenetic modification. N6-methyladenosine (m(6)A), a modification that occurs in ~30% transcripts, is dynamically regulated by writer complex (methylase) and eraser (RN...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649148/ https://www.ncbi.nlm.nih.gov/pubmed/33162550 http://dx.doi.org/10.1038/s41419-020-03143-z |