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The role of m(6)A modification in physiology and disease

Similar to DNA epigenetic modifications, multiple reversible chemical modifications on RNAs have been uncovered in a new layer of epigenetic modification. N6-methyladenosine (m(6)A), a modification that occurs in ~30% transcripts, is dynamically regulated by writer complex (methylase) and eraser (RN...

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Detalles Bibliográficos
Autores principales: Yang, Chuan, Hu, Yiyang, Zhou, Bo, Bao, Yulu, Li, Zhibin, Gong, Chunli, Yang, Huan, Wang, Sumin, Xiao, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649148/
https://www.ncbi.nlm.nih.gov/pubmed/33162550
http://dx.doi.org/10.1038/s41419-020-03143-z