Dose-Dependent and Subset-Specific Regulation of Midbrain Dopaminergic Neuron Differentiation by LEF1-Mediated WNT1/b-Catenin Signaling

The mesodiencephalic dopaminergic (mdDA) neurons, including the nigrostriatal subset that preferentially degenerates in Parkinson’s Disease (PD), strongly depend on an accurately balanced Wingless-type MMTV integration site family member 1 (WNT1)/beta-catenin signaling pathway during their developme...

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Detalles Bibliográficos
Autores principales: Nouri, Parivash, Götz, Sebastian, Rauser, Benedict, Irmler, Martin, Peng, Changgeng, Trümbach, Dietrich, Kempny, Christian, Lechermeier, Carina G., Bryniok, Agnes, Dlugos, Andrea, Euchner, Ellen, Beckers, Johannes, Brodski, Claude, Klümper, Claudia, Wurst, Wolfgang, Prakash, Nilima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649324/
https://www.ncbi.nlm.nih.gov/pubmed/33195246
http://dx.doi.org/10.3389/fcell.2020.587778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649324/
https://www.ncbi.nlm.nih.gov/pubmed/33195246
http://dx.doi.org/10.3389/fcell.2020.587778

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