Cutaneous barrier leakage and gut inflammation drive skin disease in Omenn syndrome

BACKGROUND: Severe early-onset erythroderma and gut inflammation, with massive tissue infiltration of oligoclonal activated T cells are the hallmark of Omenn syndrome (OS). OBJECTIVE: The impact of altered gut homeostasis in the cutaneous manifestations of OS remains to be clarified. METHODS: We ana...

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Detalles Bibliográficos
Autores principales: Rigoni, Rosita, Fontana, Elena, Dobbs, Kerry, Marrella, Veronica, Taverniti, Valentina, Maina, Virginia, Facoetti, Amanda, D’Amico, Giovanna, Al-Herz, Waleed, Cruz-Munoz, Mario Ernesto, Schuetz, Catharina, Gennery, Andrew R., Garabedian, Elizabeth K., Giliani, Silvia, Draper, Deborah, Dbaibo, Ghassan, Geha, Raif S., Meyts, Isabelle, Tousseyn, Thomas, Neven, Benedicte, Moshous, Despina, Fischer, Alain, Schulz, Ansgar, Finocchi, Andrea, Kuhns, Douglas B., Fink, Danielle L., Lionakis, Michail S., Swamydas, Muthulekha, Guglielmetti, Simone, Alejo, Julie, Myles, Ian A., Pittaluga, Stefania, Notarangelo, Luigi D., Villa, Anna, Cassani, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mosby 2020
Materias:
Translational and Clinical Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649331/
https://www.ncbi.nlm.nih.gov/pubmed/32311393
http://dx.doi.org/10.1016/j.jaci.2020.04.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649331/
https://www.ncbi.nlm.nih.gov/pubmed/32311393
http://dx.doi.org/10.1016/j.jaci.2020.04.005

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