Remarkable Response of EGFR- and HER2-Amplified Metastatic Colon Cancer to Pyrotinib After Failed Multiline Treatments: A Case Report and Literature Review

Human epidermal growth factor receptor 2 (HER2) has been verified as a valuable biomarker and treatment target in metastatic colorectal cancer (mCRC). Pyrotinib, a novel irreversible HER2/epidermal growth factor receptor (EGFR) dual tyrosine kinase inhibitor, can efficiently inhibit the proliferatio...

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Detalles Bibliográficos
Autores principales: Li, Hong-Shuai, Yang, Li-Li, Zhang, Ming-Yi, Cheng, Ke, Chen, Ye, Liu, Ji-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649345/
https://www.ncbi.nlm.nih.gov/pubmed/33194604
http://dx.doi.org/10.3389/fonc.2020.548867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649345/
https://www.ncbi.nlm.nih.gov/pubmed/33194604
http://dx.doi.org/10.3389/fonc.2020.548867

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