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Remarkable Response of EGFR- and HER2-Amplified Metastatic Colon Cancer to Pyrotinib After Failed Multiline Treatments: A Case Report and Literature Review

Human epidermal growth factor receptor 2 (HER2) has been verified as a valuable biomarker and treatment target in metastatic colorectal cancer (mCRC). Pyrotinib, a novel irreversible HER2/epidermal growth factor receptor (EGFR) dual tyrosine kinase inhibitor, can efficiently inhibit the proliferatio...

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Detalles Bibliográficos
Autores principales:	Li, Hong-Shuai, Yang, Li-Li, Zhang, Ming-Yi, Cheng, Ke, Chen, Ye, Liu, Ji-Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649345/ https://www.ncbi.nlm.nih.gov/pubmed/33194604 http://dx.doi.org/10.3389/fonc.2020.548867

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