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Costunolide Induces Autophagy and Apoptosis by Activating ROS/MAPK Signaling Pathways in Renal Cell Carcinoma

Although costunolide (Cos), a natural sesquiterpene compound isolated from various medicinal plants, exhibits antiproliferative and pro-apoptotic effects in diverse types of cancers, the mechanism associated with the anticancer property of Cos has not been elucidated. The present investigation was c...

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Detalles Bibliográficos
Autores principales: Fu, Dian, Wu, Ding, Cheng, Wen, Gao, Jianping, Zhang, Zhengyu, Ge, Jingping, Zhou, Wenquan, Xu, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649430/
https://www.ncbi.nlm.nih.gov/pubmed/33194716
http://dx.doi.org/10.3389/fonc.2020.582273