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A mutation in SLC20A2 (c.C1849T) promotes proliferation while inhibiting hypertrophic differentiation in ATDC5 chondrocytes

AIMS: This study aimed to investigate the effect of solute carrier family 20 member 2 (SLC20A2) gene mutation (identified from a hereditary multiple exostoses family) on chondrocyte proliferation and differentiation. METHODS: ATDC5 chondrocytes were cultured in insulin-transferrin-selenium medium to...

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Detalles Bibliográficos
Autores principales: Li, YiQiang, Lin, XueMei, Zhu, MingWei, Xun, FuXing, Li, JingChun, Yuan, Zhe, Liu, YanHan, Xu, HongWen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649514/
https://www.ncbi.nlm.nih.gov/pubmed/33135420
http://dx.doi.org/10.1302/2046-3758.911.BJR-2020-0112.R1