Mono-2-ethylhexyl phthalate drives progression of PINK1-parkin-mediated mitophagy via increasing mitochondrial ROS to exacerbate cytotoxicity

Phthalate ester plasticizers are used to improve the plasticity and strength of plastics. One of the most widely used and studied, di-2-ethylhexyl phthalate (DEHP), has been labeled as an endocrine disruptor. The major and toxic metabolic derivative of DEHP, mono-2-ethylhexyl phthalate (MEHP), is ca...

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Detalles Bibliográficos
Autores principales: Xu, Jian, Wang, Liming, Zhang, Lihuan, Zheng, Fang, Wang, Fang, Leng, Jianhang, Wang, Keyi, Héroux, Paul, Shen, Han-Ming, Wu, Yihua, Xia, Dajing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649642/
https://www.ncbi.nlm.nih.gov/pubmed/33161305
http://dx.doi.org/10.1016/j.redox.2020.101776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649642/
https://www.ncbi.nlm.nih.gov/pubmed/33161305
http://dx.doi.org/10.1016/j.redox.2020.101776

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