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Protein–fragment complex structures derived by NMR molecular replacement

Recently we have established an NMR molecular replacement method, which is capable of solving the structure of the interaction site of protein–ligand complexes in a fully automated manner. While the method was successfully applied for ligands with strong and weak binding affinities, including small...

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Detalles Bibliográficos
Autores principales: Torres, Felix, Ghosh, Dhiman, Strotz, Dean, Chi, Celestine N., Davis, Ben, Orts, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649837/
https://www.ncbi.nlm.nih.gov/pubmed/33479661
http://dx.doi.org/10.1039/d0md00068j