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Combined subthalamic and nucleus basalis of Meynert deep brain stimulation for Parkinson’s disease with dementia (DEMPARK-DBS): protocol of a randomized, sham-controlled trial
INTRODUCTION: Dementia in Parkinson’s disease (PDD) is a common non-motor symptom of advanced disease, associated with pronounced neocortical cholinergic deficits due to neurodegeneration of the nucleus basalis of Meynert (NBM) and its cholinergic terminals. In advanced PD, patients often require ad...
Autores principales: | Daniels, Christine, Steigerwald, Frank, Capetian, Philipp, Matthies, Cordula, Malzahn, Uwe, Heuschmann, Peter U., Volkmann, Jens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650115/ https://www.ncbi.nlm.nih.gov/pubmed/33324941 http://dx.doi.org/10.1186/s42466-020-00086-w |
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