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Modeling tumor development and metastasis using paired organoids derived from patients with colorectal cancer liver metastases
Tumor metastasis accounts for the majority of cancer-related deaths; it is therefore important to develop preclinical models that faithfully recapitulate disease progression. Here, we generated paired organoids derived from primary tumors and matched liver metastases in the same colorectal cancer (C...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650218/ https://www.ncbi.nlm.nih.gov/pubmed/32883331 http://dx.doi.org/10.1186/s13045-020-00957-4 |