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Campylobacter jejuni Cas9 Modulates the Transcriptome in Caco-2 Intestinal Epithelial Cells

The zoonotic human pathogen Campylobacter jejuni is known for its ability to induce DNA-damage and cell death pathology in humans. The molecular mechanism behind this phenomenon involves nuclear translocation by Cas9, a nuclease in C. jejuni (CjeCas9) that is the molecular marker of the Type II CRIS...

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Detalles Bibliográficos
Autores principales: Saha, Chinmoy, Horst-Kreft, Deborah, Kross, Inez, van der Spek, Peter J., Louwen, Rogier, van Baarlen, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650535/
https://www.ncbi.nlm.nih.gov/pubmed/33066557
http://dx.doi.org/10.3390/genes11101193