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SV40 Polyomavirus Activates the Ras-MAPK Signaling Pathway for Vacuolization, Cell Death, and Virus Release

Polyomaviruses are a family of small, non-enveloped DNA viruses that can cause severe disease in immunosuppressed individuals. Studies with SV40, a well-studied model polyomavirus, have revealed the role of host proteins in polyomavirus entry and trafficking to the nucleus, in viral transcription an...

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Detalles Bibliográficos
Autores principales: Motamedi, Nasim, Sewald, Xaver, Luo, Yong, Mothes, Walther, DiMaio, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650553/
https://www.ncbi.nlm.nih.gov/pubmed/33028008
http://dx.doi.org/10.3390/v12101128