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Estrogen Regulation of mTOR Signaling and Mitochondrial Function in Invasive Lobular Carcinoma Cell Lines Requires WNT4

SIMPLE SUMMARY: Invasive lobular carcinoma (ILC) is a common but understudied breast cancer subtype. ILC is presumed to be a low-risk disease in part because nearly all ILCs contain the estrogen receptor (ER). However, we previously showed that ER has unique functions in ILC cells, including driving...

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Detalles Bibliográficos
Autores principales: Shackleford, Madeleine T., Rao, Deviyani M., Bordeaux, Evelyn K., Hicks, Hannah M., Towers, Christina G., Sottnik, Joseph L., Oesterreich, Steffi, Sikora, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650584/
https://www.ncbi.nlm.nih.gov/pubmed/33053661
http://dx.doi.org/10.3390/cancers12102931