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Integrated Transcriptome and Proteome Analyses Reveal the Regulatory Role of miR-146a in Human Limbal Epithelium via Notch Signaling

MiR-146a is upregulated in the stem cell-enriched limbal region vs. central human cornea and can mediate corneal epithelial wound healing. The aim of this study was to identify miR-146a targets in human primary limbal epithelial cells (LECs) using genomic and proteomic analyses. RNA-seq combined wit...

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Detalles Bibliográficos
Autores principales: Poe, Adam J., Kulkarni, Mangesh, Leszczynska, Aleksandra, Tang, Jie, Shah, Ruchi, Jami-Alahmadi, Yasaman, Wang, Jason, Kramerov, Andrei A., Wohlschlegel, James, Punj, Vasu, Ljubimov, Alexander V., Saghizadeh, Mehrnoosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650592/
https://www.ncbi.nlm.nih.gov/pubmed/32993109
http://dx.doi.org/10.3390/cells9102175