Single Amino Acid Substitutions Surrounding the Icosahedral Fivefold Symmetry Axis Are Critical for Alternative Receptor Usage of Foot-and-Mouth Disease Virus

The integrins function as the primary receptor molecules for the pathogenic infection of foot-and-mouth disease virus (FMDV) in vivo, while the acquisition of a high affinity for heparan sulfate (HS) of some FMDV variants could be privileged to facilitate viral infection and expanded cell tropism in...

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Detalles Bibliográficos
Autores principales: Gong, Xiao-Hua, Bai, Xing-Wen, Li, Ping-Hua, Bao, Hui-Fang, Zhang, Meng, Chen, Ying-Li, Sun, Pu, Yuan, Hong, Huang, Lei, Ma, Xue-Qing, Fu, Yuan-Fang, Cao, Yi-Mei, Li, Kun, Zhang, Jing, Li, Zhi-Yong, Li, Dong, Lu, Zeng-Jun, Liu, Zai-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650640/
https://www.ncbi.nlm.nih.gov/pubmed/33050303
http://dx.doi.org/10.3390/v12101147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650640/
https://www.ncbi.nlm.nih.gov/pubmed/33050303
http://dx.doi.org/10.3390/v12101147

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