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Single Amino Acid Substitutions Surrounding the Icosahedral Fivefold Symmetry Axis Are Critical for Alternative Receptor Usage of Foot-and-Mouth Disease Virus
The integrins function as the primary receptor molecules for the pathogenic infection of foot-and-mouth disease virus (FMDV) in vivo, while the acquisition of a high affinity for heparan sulfate (HS) of some FMDV variants could be privileged to facilitate viral infection and expanded cell tropism in...
Autores principales: | Gong, Xiao-Hua, Bai, Xing-Wen, Li, Ping-Hua, Bao, Hui-Fang, Zhang, Meng, Chen, Ying-Li, Sun, Pu, Yuan, Hong, Huang, Lei, Ma, Xue-Qing, Fu, Yuan-Fang, Cao, Yi-Mei, Li, Kun, Zhang, Jing, Li, Zhi-Yong, Li, Dong, Lu, Zeng-Jun, Liu, Zai-Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650640/ https://www.ncbi.nlm.nih.gov/pubmed/33050303 http://dx.doi.org/10.3390/v12101147 |
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