Stress Granule Assembly Can Facilitate but Is Not Required for TDP-43 Cytoplasmic Aggregation

Stress granules (SGs) are hypothesized to facilitate TAR DNA-binding protein 43 (TDP-43) cytoplasmic mislocalization and aggregation, which may underly amyotrophic lateral sclerosis pathology. However, much data for this hypothesis is indirect. Additionally, whether P-bodies (PBs; related mRNA-prote...

Descripción completa

Detalles Bibliográficos
Autores principales: Fernandes, Nikita, Nero, Luke, Lyons, Shawn M., Ivanov, Pavel, Mittelmeier, Telsa M., Bolger, Timothy A., Buchan, J. Ross
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650667/
https://www.ncbi.nlm.nih.gov/pubmed/32992901
http://dx.doi.org/10.3390/biom10101367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650667/
https://www.ncbi.nlm.nih.gov/pubmed/32992901
http://dx.doi.org/10.3390/biom10101367

Ejemplares similares