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Stress Granule Assembly Can Facilitate but Is Not Required for TDP-43 Cytoplasmic Aggregation

Stress granules (SGs) are hypothesized to facilitate TAR DNA-binding protein 43 (TDP-43) cytoplasmic mislocalization and aggregation, which may underly amyotrophic lateral sclerosis pathology. However, much data for this hypothesis is indirect. Additionally, whether P-bodies (PBs; related mRNA-prote...

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Detalles Bibliográficos
Autores principales:	Fernandes, Nikita, Nero, Luke, Lyons, Shawn M., Ivanov, Pavel, Mittelmeier, Telsa M., Bolger, Timothy A., Buchan, J. Ross
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650667/ https://www.ncbi.nlm.nih.gov/pubmed/32992901 http://dx.doi.org/10.3390/biom10101367

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