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Effects of gp120 Inner Domain (ID2) Immunogen Doses on Elicitation of Anti-HIV-1 Functional Fc-Effector Response to C1/C2 (Cluster A) Epitopes in Mice

Fc-mediated effector functions of antibodies, including antibody-dependent cytotoxicity (ADCC), have been shown to contribute to vaccine-induced protection from HIV-1 infection, especially those directed against non-neutralizing, CD4 inducible (CD4i) epitopes within the gp120 constant 1 and 2 region...

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Detalles Bibliográficos
Autores principales: Sherburn, Rebekah, Tolbert, William D., Gottumukkala, Suneetha, Beaudoin-Bussières, Guillaume, Finzi, Andrés, Pazgier, Marzena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650682/
https://www.ncbi.nlm.nih.gov/pubmed/32998443
http://dx.doi.org/10.3390/microorganisms8101490