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Comparative Analysis of Thrombin Calibration Algorithms and Correction for Thrombin-α2macroglobulin Activity

Background: The thrombin generation (TG) test is useful for characterizing global hemostasis potential, but fluorescence substrate artifacts, such as thrombin-α2macroglobulin (T-α2MG) signal, inner filter effect (IFE), substrate consumption, and calibration algorithms have been suggested as sources...

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Detalles Bibliográficos
Autores principales: Chang, William C., Jackson, Joseph W., Machlus, Kellie R., Wolberg, Alisa S., Ovanesov, Mikhail V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650706/
https://www.ncbi.nlm.nih.gov/pubmed/32987791
http://dx.doi.org/10.3390/jcm9103077