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Pharmacological Modulation of Blood–Brain Barrier Permeability by Kinin Analogs in Normal and Pathologic Conditions

The blood–brain barrier (BBB) is a major obstacle to the development of effective diagnostics and therapeutics for brain cancers and other central nervous system diseases. Peptide agonist analogs of kinin B1 and B2 receptors, acting as BBB permeabilizers, have been utilized to overcome this barrier....

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Detalles Bibliográficos
Autores principales: Sikpa, Dina, Whittingstall, Lisa, Savard, Martin, Lebel, Réjean, Côté, Jérôme, McManus, Stephen, Chemtob, Sylvain, Fortin, David, Lepage, Martin, Gobeil, Fernand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650794/
https://www.ncbi.nlm.nih.gov/pubmed/33003415
http://dx.doi.org/10.3390/ph13100279