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Pharmacological Modulation of Blood–Brain Barrier Permeability by Kinin Analogs in Normal and Pathologic Conditions
The blood–brain barrier (BBB) is a major obstacle to the development of effective diagnostics and therapeutics for brain cancers and other central nervous system diseases. Peptide agonist analogs of kinin B1 and B2 receptors, acting as BBB permeabilizers, have been utilized to overcome this barrier....
Autores principales: | Sikpa, Dina, Whittingstall, Lisa, Savard, Martin, Lebel, Réjean, Côté, Jérôme, McManus, Stephen, Chemtob, Sylvain, Fortin, David, Lepage, Martin, Gobeil, Fernand |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650794/ https://www.ncbi.nlm.nih.gov/pubmed/33003415 http://dx.doi.org/10.3390/ph13100279 |
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