The rate of dasotraline brain entry is slow following intravenous administration

RATIONALE: Drugs that rapidly increase dopamine levels have an increased risk of abuse. Dasotraline (DAS) is a dopamine and norepinephrine reuptake inhibitor characterized by slow oral absorption with low potential for abuse. However, it remains unclear whether intravenous (i.v.) administration woul...

Descripción completa

Detalles Bibliográficos
Autores principales: Lew, Robert, Constantinescu, Cristian C., Holden, Daniel, Carson, Richard E., Carroll, Vincent, Galluppi, Gerald, Koblan, Kenneth S., Hopkins, Seth C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7651685/
https://www.ncbi.nlm.nih.gov/pubmed/32813030
http://dx.doi.org/10.1007/s00213-020-05623-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7651685/
https://www.ncbi.nlm.nih.gov/pubmed/32813030
http://dx.doi.org/10.1007/s00213-020-05623-8

Ejemplares similares