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Lack of sphingomyelin synthase 2 reduces cerebral ischemia/reperfusion injury by inhibiting microglial inflammation in mice

Recanalization of blood flow after ischemia can lead to ischemia/reperfusion injury, and inflammation plays an important role in the mechanisms behind cerebral ischemia/reperfusion injury. Sphingomyelin synthase 2 (SMS2) deficiency reduces inflammation; however, the effect and mechanism of action of...

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Detalles Bibliográficos
Autores principales: Yang, Yu, Hu, Fengxian, Yang, Guifeng, Meng, Qingmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7651782/
https://www.ncbi.nlm.nih.gov/pubmed/33178339
http://dx.doi.org/10.3892/etm.2020.9371