Cargando…

Sophocarpine attenuates septic liver injury through suppression of the NLRP3 inflammasome via autophagy-mediated degradation

Septic liver injury remains a challenge in sepsis treatment. Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3 (NLRP3) inflammasome activation has been suggested to be a major cause of hepatocyte cell death in liver diseases. However, insufficient research...

Descripción completa

Detalles Bibliográficos
Autores principales: Hou, Nianguo, Dai, Xiaofeng, Lu, Wenqing, Yang, Hongguang, Yu, Haida, Liu, Junchao, Li, Hui, Shuai, Xunjun, Ai, Dengbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7651882/
https://www.ncbi.nlm.nih.gov/pubmed/33178347
http://dx.doi.org/10.3892/etm.2020.9379