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Homoharringtonine Exerts an Antimyeloma Effect by Promoting Excess Parkin-Dependent Mitophagy

PURPOSE: Homoharringtonine (HHT) has been used as an antileukemia agent in the clinic which processes a high-potential therapeutic efficacy against multiple myeloma (MM). In this study, we investigated the antimyeloma mechanism of HHT. METHODS: Three MM cell lines and a xenograft model were applied....

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Detalles Bibliográficos
Autores principales: Zhang, Yanyu, Huang, Ning, Xu, Jie, Zheng, Wei, Cui, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652225/
https://www.ncbi.nlm.nih.gov/pubmed/33177810
http://dx.doi.org/10.2147/DDDT.S279054