Ethanol-induced CYP2E1 Expression is Reduced by Lauric Acid via PI3K Pathway in HepG2 Cells

The metabolism of alcohol involves cytochrome P450 2E1 (CYP2E1)-induced oxidative stress, with the association of phosphatidylinositol-3-kinases (PI3K) and nuclear factor kappa B (NFκB) signalling pathways. CYP2E1 is primarily involved in the microsomal ethanol oxidising system, which generates mass...

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Detalles Bibliográficos
Autores principales: Lua, Ying-Huan, Ong, Wei-Wah, Wong, Hong-Kin, Chew, Choy-Hoong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Penerbit Universiti Sains Malaysia 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652244/
https://www.ncbi.nlm.nih.gov/pubmed/33214856
http://dx.doi.org/10.21315/tlsr2020.31.3.5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652244/
https://www.ncbi.nlm.nih.gov/pubmed/33214856
http://dx.doi.org/10.21315/tlsr2020.31.3.5

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