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Impact of subinhibitory concentrations of metronidazole on proteome of Clostridioides difficile strains with different levels of susceptibility

Clostridioides difficile is responsible for various intestinal symptoms from mild diarrhea to severe pseudomembranous colitis and is the primary cause of antibiotic-associated diarrhea in adults. Metronidazole was the first-line treatment for mild to moderate C. difficile infections for 30 years. Ho...

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Detalles Bibliográficos
Autores principales: Doan, Tri-Hanh-Dung, Yen-Nicolaÿ, Stéphanie, Bernet-Camard, Marie-Françoise, Martin-Verstraete, Isabelle, Péchiné, Séverine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652271/
https://www.ncbi.nlm.nih.gov/pubmed/33166349
http://dx.doi.org/10.1371/journal.pone.0241903