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Effect of drug dose and timing of treatment on the emergence of drug resistance in vivo in a malaria model
BACKGROUND AND OBJECTIVES: There is a significant interest in identifying clinically effective drug treatment regimens that minimize the de novo evolution of antimicrobial resistance in pathogen populations. However, in vivo studies that vary treatment regimens and directly measure drug resistance e...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652304/ https://www.ncbi.nlm.nih.gov/pubmed/33209305 http://dx.doi.org/10.1093/emph/eoaa016 |