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Analysis of endogenous and exogenous tumor upregulated promoter expression in canine tumors

Gene therapy is a promising treatment option for cancer. However, its utility may be limited due to expression in off-target cells. Cancer-specific promoters such as telomerase reverse transcriptase (TERT), survivin, and chemokine receptor 4 (CXCR4) have enhanced activity in a variety of human and m...

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Detalles Bibliográficos
Autores principales: Sajib, Abdul Mohin, Sandey, Maninder, Morici, Samantha, Schuler, Bradley, Agarwal, Payal, Smith, Bruce F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652315/
https://www.ncbi.nlm.nih.gov/pubmed/33166332
http://dx.doi.org/10.1371/journal.pone.0240807